mini girl Posted July 19, 2012 Share Posted July 19, 2012 Breeder friend rang to ask if I had heard of renal dysplasia DNA test for miniature poodles have searched the net not a real lot on it to tell the truth this friend has been breeding for nearly 40 years and has not come across it in any of her pups produced. Nor have I with around 75 pups out there and no report on any of them with this the reason she was enquiring was she had been approached for use of one of her stud boys and was asked if he was clear of this she was also given email for ASAP labs who do the test have not heard great things about them to tell the truth but does anyone have any knowledge of this test especially for miniature poodles. Found some mention of it on line for standard poodles. Link to comment Share on other sites More sharing options...
poodlesrule Posted July 19, 2012 Share Posted July 19, 2012 Breeder friend rang to ask if I had heard of renal dysplasia DNA test for miniature poodles have searched the net not a real lot on it to tell the truth this friend has been breeding for nearly 40 years and has not come across it in any of her pups produced. Nor have I with around 75 pups out there and no report on any of them with this the reason she was enquiring was she had been approached for use of one of her stud boys and was asked if he was clear of this she was also given email for ASAP labs who do the test have not heard great things about them to tell the truth but does anyone have any knowledge of this test especially for miniature poodles. Found some mention of it on line for standard poodles. Hi Mini girl, ASAP Labs actually send the test to Dogenes in the USA for the test. Have heard that they can get false positives. https://www.dogenes.com/ Check out this link for more info. Link to comment Share on other sites More sharing options...
zenchel Posted July 20, 2012 Share Posted July 20, 2012 Below is a statement that Dogs Victoria Canine Health Committee prepared after enquiries about the DNA test relating to Renal Dysplasia. Renal Dysplasia is of concern in several breeds, including Standard Poodles, Miniature Schnauzers, Soft Coated Wheaten Terriers, Cocker Spaniels and most commonly Lhasa Apsos and Shih Tzus. The only way to definitively diagnose the presence and severity of the disease is by wedge biopsy. There is a DNA test available that appears to test for Cox-2 alleles, and not RD per se. The information accompanying the test doesn't definitively demonstrate these alleles are in themselves sufficient to develop RD. Publication has been a long time coming following availability of the test. The concern is that the DNA test identifies factors that may be necessary, but are not sufficient by themselves, for expression of disease... so how useful are they -- what sort of predictive power is there that an animal identified as having these 'disease alleles' will be affected by this disease? These issues leave the impression that information gained from the DNA test may be useful, in conjunction with other diagnostic procedures including wedge biopsies, to a breeder that finds they have a problem with Renal Dysplasia, however the DNA test in isolation does not qualify as “the answer”. Sylvia Power Chair DV Canine Health Committee Link to comment Share on other sites More sharing options...
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