

sandgrubber
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Everything posted by sandgrubber
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Not to mention that EIC rarely occurs without heavy exercise . . . most affected dogs (ie, dogs with a double dose of the faulty gene) are never symptomatic. I wouldn't worry about the long rib cage / short coupling. Labs are supposed to be short coupled, and it generally doesn't interfere with their packing on weight. I agree with others about no more than two meals a day and cutting the canned . . . especially catfood. Chicken mince is fine, especially if it was made for dogs (includes bones) and you don't cook it. Then either going the raw food . . . or quality dry food route . . . or some combination. If you dog is happy eating carrots, he is hungry. You are starving him. Personally, I'd correct the diet first . . . if that goes nowhere, I'd work with a good vet.
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Aloe Vera Causes Fertility Issues In Stud Dogs
sandgrubber replied to dog geek's topic in Breeders Community
In my experience, dogs will not eat aloe vera or drink its juice. I certainly wouldn't. Tastes awful! Does anyone know how much 200 mg/kg is in relation to amounts put in the occasional dog treat that includes aloe vera? -
+1 see http://www.naybesa.com/?p=3733 for additional info and pictures (and some atrocious spelling). Seems there's suggestion that Cocaine was well fenced and someone let him out, and some witnesses saw no attacks on children . . . cute looking pup.
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$1.4 Million + To Minimize Drug Testing On Dogs
sandgrubber replied to sandgrubber's topic in In The News
'This obscenity' is not going to cease, unless some major technological breakthrough makes it obsolete or political pressure gets overwhelming. It's good to see forces relatively close to the industry working to decrease the extent and minimize the damage. -
I think many geneticists feel that subspecies are not valid taxa unless backed by genetic evidence. You'll find people from Wayne's group identify by haplotype and geographic origin, but rarely use Latin subspecies names. I suspect they'd say their way is more scientific than carrying the classification past Canis lupus. Most of their Middle Eastern wolf DNA came from Isreal, and their results seem to show the Isreali wolf population to be heterogeneous . . . . if I'm reading correctly. I think it was Retrieverman who brought in the subspecies names.
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I'm sure that has happened. But it is still a concern if police are in effect using the dog as a means to search without a warrant. Have a read of this . . . http://www.springerlink.com/content/j477277481125291/fulltext.html dogs will give false positives when there's nothing, and the thing they signal is affected by the handler. And I have little doubt that dogs can be trained not to give false positives.
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Oops, You're right on two counts. The paper is a year old . . . I didn't notice the date. The more recent paper is Bridgett M. vonHoldt, John P. Pollinger1, Dent A. Earl2,et al, 2011, A genome-wide perspective on the evolutionary history of enigmatic wolf-like canids, Genome Research in May 2011. I can't access Genomic Research, but Discover Magazine published a lay version. http://blogs.discovermagazine.com/gnxp/2011/05/a-map-of-charismatic-canid-genomic-variation/ This doesn't really address the geography of dog origins . . . more focus on wolf x coyote mixing in North America. It does show PCA results separating the dog cluster and various wolf population clusters. This suggests dogs are closest to Southern Europe or the Middle East. Looks like the first two dimensions in the PCA didn't explain a high percent of the variance, which if I remember my stats raises doubts.
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According to more recent study, it's more complex. I think they're finding that, as you might expect, the original semi-domesticated or domesticated dogs crossed out to other wolf populations along the migration route. They didn't worry much about pedigrees in prehistory, nor was it easy to confine a bitch on season . . . . so you'd expect that the local boys would inject DNA as dogs migrated from the Middle East through South Asia to Australia.
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Published online 28 June 2011 | Nature 474, 551 (2011) | doi:10.1038/474551a News Call to curb lab tests on dogs Canine remains the default option in outdated pharmaceutical toxicology. Marian Turner Dogs make popular laboratory subjects, with uses including drug-toxicity testing, above.Y. Forestier/CorbisMan's best friend bears a heavy burden in the pharmaceutical industry. Every year, tens of thousands of dogs are subjects in drug-toxicity studies in Europe and the United States, even though many scientists think that they are poor predictors of drug effects in humans. Discussions on this sensitive issue have now been opened up by a hefty donation from Hildegard Doerenkamp, a Swiss philanthropist and passionate dog-lover, to the Zurich-based Doerenkamp–Zbinden Foundation, which supports work to reduce animal testing. Toxicology researchers from academia and industry, and animal-welfare groups met in Budapest last week to develop an action plan and discuss how to spend Doerenkamp's donation of more than €1 million (US$1.4 million) to drive change. Scientists need to identify what information dog tests provide that tests in vitro or on rodent species cannot, they say. And regulatory authorities such as the US Food and Drug Administration (FDA) and the European Medicines Agency need to harmonize their requirements for dog testing so that pharmaceutical companies can minimize the number of animals they use. Regulatory authorities usually require that drugs are tested for toxicity in both a rodent and a non-rodent species. The latter tends to be dogs, because they are readily available, easy to handle and in many ways physiologically similar to humans. Pharmaceutical testing accounts for around three-quarters of all dogs used in science. But scientists inside and outside industry say that dogs are not always the best option for testing and could, in some cases, be replaced by in vitro tests. In spite of these reservations, and public disquiet over the use of dogs in testing, very little has been done to curb the practice, says Thomas Hartung, a molecular toxicologist and head of the Centre for Alternatives to Animal Testing (CAAT) at Johns Hopkins University in Baltimore, Maryland, which organized the meeting. Regulatory agencies are nervous of changing procedures. Any adverse reactions to a new drug, for example, could be blamed on new tests failing to spot dangers. Only if a battery of in vitro alternatives can match the level of toxicity prediction that dogs can provide will regulators agree to a change, says Hartung. So far only one such test — used to predict whether a compound could lead to cardiac arrhythmias — comes close, but it has not yet been internationally validated. In its action plan, to be published in the next few months, CAAT will call for the setting up of a database of dog-test results to help to identify more targets for in vitro tests by highlighting physiological effects seen only in dogs. It will also call for a better definition of those tests for which dogs provide the best model, and those for which another species — such as the mini-pig — should be used instead. Toxicologist Georg Schmitt of Hoffmann La-Roche in Basel, Switzerland, says that pharmaceutical companies should not use dogs by default simply because facilities and test protocols exist. "Dogs can be oversensitive to some compounds, such as hormones, and their gastrointestinal system behaves differently to that of humans," says Schmitt. He says that studies in which dogs have proved to be poor models should be published. The full article is posted with free access on nature.com . . . but you need to sign up and sign in to get to it.
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New Finding Puts Origins of Dogs in Middle East By NICHOLAS WADE Borrowing methods developed to study the genetics of human disease, researchers have concluded that dogs were probably first domesticated from wolves somewhere in the Middle East, in contrast to an earlier survey suggesting dogs originated in East Asia. Enlarge This Image Julie Fletcher/Getty Images The dingo was one of the breeds studied to determine where dogs were first domesticated from wolves. Multimedia Graphic From Ancestral Wolf to Modern Dog This finding puts the first known domestication — that of dogs — in the same place as the domestication of plants and other animals, and strengthens the link between the first animal to enter human society and the subsequent invention of agriculture about 10,000 years ago. A Middle Eastern origin for the dog also fits in better with the archaeological evidence, and has enabled geneticists to reconstruct the entire history of the dog, from the first association between wolves and hunter gatherers some 20,000 years ago to the creation by Victorian dog fanciers of many of today's breeds. A research team led by Bridgett M. vonHoldt and Robert K. Wayne of the University of California, Los Angeles, has analyzed a large collection of wolf and dog genomes from around the world. Scanning for similar runs of DNA, the researchers found that the Middle East was where wolf and dog genomes were most similar, although there was another area of overlap between East Asian wolves and dogs. Wolves were probably first domesticated in the Middle East, but after dogs had spread to East Asia there was a crossbreeding that injected more wolf genes into the dog genome, the researchers conclude in Thursday's issue of the journal Nature. The archaeological evidence supports this idea, since some of the earliest dog remains have been found in the Middle East, dating from 12,000 years ago. The only earlier doglike remains occur in Belgium, at a site 31,000 years old, and in western Russia from 15,000 years ago. . .. for full article and illustrations see http://www.nytimes.c...nce/18dogs.html a news treatment of the previous theory (2002), apparently bumped by this one, can be found at http://news.bbc.co.uk/2/hi/science/nature/2498669.stm
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As posted above, I wrote to the Green MP involved. He replied saying there was a misunderstanding. Dogs are not being used as a replacement for a more invasive search, they are being used as a justification for a more invasive search. The dog signals. The police, in effect, have a warrant and can go ahead with the search. Statistical review shows a very high rate of false positives here: dogs signal, police search and find nothing. There is ample evidence, including scientific study, to show that handlers can affect their dogs, and direct their signalling in the case where there is no real scent trigger. I think this IS a problem. Police can use dogs to justify almost any search. It's a violation of civil rights . . . and a sign of poor dog training. I'd think that if dogs were given strong rewards for finding nothing when there was nothing to find . . . and false positives were not rewarded at all . . . not even by the excitement of watching some suspect get searched . .. that the false positive rate would plummet. I'd guess this could be implemented very simply by putting handler/officers on probation is they run up too many false positives and suspending them if the problem continues. In sum, there is a problem. No need to dump the dogs . . . who have unquestionably high ability to detect scent, plus being much cheaper and more portable than electronic scent detection equivalents. That would be like dumping the judiciary because judges had been writing too many search warrants when there was nothing to find. Better to set up a reward structure that recognises that false positives are a problem.
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Another observation from Retrieverman. . .. and another weakness in ethology studies linking dog behaviour to wolf behaviour. for full article see http://retrieverman....c-dog/#comments The primary ancestors of the domestic dog July 11, 2011 by retrieverman Canis lupus arabs– the Arabian wolf: And Canis lupus pallipes– the Iranian wolf: According to recent genome-wide analysis, most domestic dogs share many more genetic markers with Middle Eastern wolves than with any other subspecies. Arabian wolves weigh 25-55 pounds. Arabian wolves have the same "small dog" gene that causes very small size in domestic dogs. They also have the fused middle toes on the front feet, a trait they share with basenjis. Iranian wolves go 55-70 pounds, rough the same size as a typical golden retriever. Neither of these wolves are the big "moose-killer" wolves from the northern parts of Eurasia and North America that every knows so well, that everyone sees in zoos, and that everyone thinks are the primary ancestors of the domestic dogs. Research that in anyway compares dogs to these wolves is methodological murky, for these wolves are actually quite specialized in their behavior. These smaller Middle Eastern wolf subspecies are much more generalist in their behavior and prey choices. It might be a better study to compare "primitive" domestic dogs, like dingoes and basenjis, with these wolves. . .. posting the newspaper version of this in the News section . . . when I posted this I hadn't noticed that it was actually a News item and the Retrieverman Blog is commenting on that news.
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If some of these animal rights orgs ever get their way, you can say goodbye to your companion dog, may as well replace It now with a hardy stuffed toy! I'm sure It can be a great companion for you and It's rights will never be violated! Take away a working dogs ability to work and you may as well kill them all, Is that what you want What do you suppose will happen if all these dogs were just companions? Sure some may very well adapt to a life of sleeping and eating, but I guarantee many won't! I've said It before every dog has a purpose, take away that purpose and you'll be left with nothing let alone a companion Your right about the animal groups. Dogs are what we make them. Pits are no more natural fighters than GSDs are natural, shepherds. Agility would be better for dogs than seeing them blown to bits on the battlefield. I was taught the Golden Rule (do as you would be done by). I'd rather be blown to bits in my prime doing something that I found satisfying than live to a lonely, depressed, miserable ripe-old age with little that satisfies my inbuilt desires. The dogs to feel sorry for are the social animals kept in solitary confinement in someone's back yard for the duration of their life.
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Animal Welfare Groups Say Australian Dogs Are Being 'sold Into Mis
sandgrubber replied to SwaY's topic in In The News
get rid of puppy farming and this problem would go away. I exported two pups to Singapore . . . both to wealthy ex-pat businessmen who were unable to find acceptable Labradors in Asia and turned to Oz cause quarantine is to be avoided for young pups. In researching the process I found some parts of AQIS disgustingly pro-export . . . like, all foreign exchange earnings are good. Wouldn't surprise me if there were some 'regular' exporters who have set up 'efficient' mechanisms for bulk export. -
Mobile vets are great and will often give good discounts for a full litter. Figure. They pay $5/vac. It takes an hour or so. If they make $20/pup, a litter of 12 returns a pretty good wage.
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My two Lab girls alert bark . . . to flying plastic bags, garbage cans that have been put in something other than their usual place, kids roughhousing next door. Also, if I say 'hello' in a loud voice, they go sailing out the door barking and looking for something to bark at. But I've had people come right up to the door and they just go out and wag and ask for attention, quietly. I'm ok with this. When they bark, they just bark once or twice . . . and the neighbors are happy with the noise level.
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Breeders are obliged to 'improve the breed' . . . but there are many opinions about what constitutes an improvement. It's important to educate yourself about your breed and about dogs, dog health, dog behaviour, and dog genetics. Showing has both positives and negatives. It allows you to see lots of other dogs and get to know people in your breed circle. It teaches you how judges are interpreting the breed standard . . . sometimes this is confusing because they don't justify their evaluations and a lot of things seem arbitrary. It may also inculcate a sort of "show blindness" that makes you compete to achieve the modern ideal for conformation and turn your attention away from temperament and health. I think it is more important, as a breeder, to formulate where you want to go with your breed, and the ability to look critically at dogs based on your ideals than it is to be a showie. Eg, if you are not worried about eye colour or tail-set, but are very concerned about whether dogs are calm and make good family members, or whether they can herd sheep, you will find shows are helpful to a degree, but that they wear thin after awhile. If you ever develop kennel blindness and cannot see the faults you would like to improve upon in your dogs, you should hang up your hat as a breeder. But you can critically appreciate dogs without being a showie.
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Was the hose for the kids, or the dogs? I assume it's past the point where you could invite the kids to take a walk with you and your dogs sometime to start building something other than malice. I once had neighbour kids who teased cause they were afraid of my dogs and didn't know how to handle their fear. They were fine after they met the dogs and played a few games of fetch. But it sounds like the father is the real problem . . . and the situation is pretty far gone.
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Should also consider the genetic factor. Labs are obesity-prone. To me this is a genetic defect, as much as tendency to OCD or HD. Could easily owe to breed history. Labradors are bred from land race that served many functions in the cold coastal regions of Newfoundland and Labrador [Canada]. These dogs were a bit like marine mammals in that they had to face the metabolic challenges of swimming in cold water, and spending a lot of time in freezing temperatures while wet. Evolution has found a good solution to this metabolic challenge . . .blubber. Ok, you can find lots of pictures of slim-and-trim 3 year old Labs doing agility or fetching game. Bfd. Find the same dogs at 10 years. I'll bet most of them aren't so svelt. And lots of Labs end out in family situations where there's some, but not lots, exercise. It's easy to blame the owner / puppy buyer. I think, for the long term good of the breed, Lab breeders need to recognize there's a genetic tendency to obesity, and to look for ways to correct this problem.
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Poor Snowflake, and poor owner! It's criminal that the police don't make this a priority. For a lot of us, the dog is family, and dog theft amounts to kidnap. Especially horrid for bull breeds, where the owner may have real, or inflated, fears that the dog has gone to a dog fighting ring. Awful, awful, awful, awful.
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Legal Safeguards Hit Backyard Dog Breeder Fay Armstrong
sandgrubber replied to pie's topic in In The News
Sometimes it takes work to get democratic systems to work. But my guess is that IF people lean on key people in the system (organizers need to identify key people and encourage people to contact them) with the result that a few people get big fines, dogs removed, and / or get thrown in jail, backyard breeders, puppy mills, and pet shops will start toeing the line with respect to health checks and diseased pups. -
Great system. If it works. Somebody want a good small business . . . try renting these devices to people with Houdini's. 'For less than a dollar a day, you can keep track of your escape artist' . . .. at $29.95/mo the thing will pay for itself in less than 10 months . . .put people on a 24 month contract like the phone companies do and you've got a license to print money!
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email sent to [email protected] You might want to look at the negative reaction to your policy on sniffer dogs. See: http://www.dolforums.com.au/topic/223357-the-greens-say-get-rid-of-sniffer-dogs/ key points * the statistics provided may show a good 'find' rate * most people would rather have a quick sniff over by a dog than have a policeman have them turn out their pockets, ramsack their house, search their car, etc. * you need to compare success of humans without dogs to success of humans working with dogs to do a fair analysis. I'd encourage people to send email to shoebridge as well as posting . . . no point preaching to the choir. [i'm one of those people who would like to be green, and it bugs the hell out of me to see Green representatives taking idiotic stances. The environment needs protection. I wish these idiots would do a better job on their core mission and stop playing footsie with the animal rights crowd.]
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Pedigree Dog Segment On The 7pm Project
sandgrubber replied to huski's topic in General Dog Discussion
Another sad thing about the database is that the more common the breed, the more diseases you find reported. Look at, say, the Golden Retriever, which ranks at near the top of the list for having a broad genetic base in Canine Genome work. You'd think the breed was in deep trouble from the list . . . Factor VIII Deficiency Haemolytic Anaemia Haemophilia A Hemangiosarcoma Lymphosarcoma Sub-Aortic Stenosis Diabetes Mellitus Hypothyroidism Lymphocytic thyroiditis Thyroiditis Allergies Hepatic Encephalopathy, Portosystemic. Hepatitis, Chronic Active Protein losing enteropathy Acral lick dermatitis Acute moist dermatitis Allergies Atopy Dermatitis, atopic Ectropion Entropion Folliculitis Furunculosis Granulomatous sebaceous adenitis Hemangiosarcoma Juvenile cellulitis Pododermatitis Sebaceous adenitis Vitiligo Fragmented Coronoid Process Hip Dysplasia Muscular Dystrophy Myasthenia Gravis Osteochondritis dissecans Osteochondrosis dissecans Behavioral abnormalities Cataract Coloboma Corneal Dystrophy Distichiasis Optic nerve hypoplasia, bilateral Persistent pupillary membrane Polyneuropathy, distal sensorimotor Progressive Retinal Atrophy (PRA) (X-linked) Vogt-Koyanagi-Harada-like syndrome Allergies Pyometra Renal Dysplasia Compare to the Blue Tick Coonhound . . . uncommon in Australia. .. looks like a really healthy breed, only four hereditary diseases, yah, right . Osteochondritis dissecans Osteochondrosis dissecans Globoid cell leukodystrophy Lysosomal Storage Disease A general public breed site says The Bluetick coonhound is a relatively healthy breed but keep an eye out for eye problems (catarracts), hip dysplasia, bloating, hypothyroidism, and luxating patellas. An insurance site says " hip dysplasia, luxating patellas and autoimmune thyroiditis. They may also be prone to bloat. Other sources add Krabbes disease and prone-ness to ear infections. All sources mention HD, which USydney doesn't pick up, no source mentions any of the four (or three, if you count OCD as one disease) problems U Sydney lists. The U Sydney group freely admits that their data say nothing about frequency: "The importance of disorders described in the LIDA catalogue varies in terms of frequency and severity. " -
I'd guess it's reversible, but reversing may take an investment in time they don't have. When you say 3 hrs a day, is that 3 quality hours, or just 3 hrs being in the house when the dogs are there . . . and the rest of the time the dogs are alone. If it's quality time, I'd say they could fix things with a bit of help, unless the pup has a built-in temperament that isn't people friendly. Simply separating the dogs is likely to produce separation anxieties . . . maybe they can find someone to help them figure out how to make being alone with them fun for the pup. I feel a bit sorry for the Lab, too.