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sterlingsilver

Stem Cell Research

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I have heard a lot about stem cell research in dogs and thought it was the next big thing, but recently I have been told it may not be.

Has anyone has any success with this procedure?

How expensive were the treatments?

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More information? Treatments for what, exactly? :) Stem cell research can be applied to plenty different things. Like they're doing stem cell research at the moment to try and actually regrow skin for burn victims and I heard they just recently succeeded with regrowing a dog's pads that had been completely burnt off.

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Do you mean for hip dysplasia? Costs about $2500 last time I looked into it, and they haven't yet done clinic trials proving that it actually works. Can't wait for them to actually do proper robust studies on it - I hope they do.

I might take a chance on it if I owned a seriously arthritic dog and some spare cash, but couldn't recommend it yet to anyone else.

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Went to a information night ran by a clinic in Lilydale (VIC) about 3 weeks ago. They are doing stem cell therapy on dogs,cats and horses with arthritis, hip dysplasia and other ligaments/tendon problems. They said the results so far were extremely positive and had two dogs at the night that had the procedure. I've got my lab booked in for the stem cell next month.

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Do you mean for hip dysplasia? Costs about $2500 last time I looked into it, and they haven't yet done clinic trials proving that it actually works. Can't wait for them to actually do proper robust studies on it - I hope they do.

I might take a chance on it if I owned a seriously arthritic dog and some spare cash, but couldn't recommend it yet to anyone else.

+1

Totally agree with everything said.

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I meant in general, treatment for any condition.

I heard there had been trials, but no positive outcomes.

I know of a couple vets that have taken it on board and are treating clients pets, but havent heard of anyone....yet...that had thought the cost worthwhile.

The latest I heard from another vet is that it had not proved successful overall, and there were not enough positive outcomes to say it works.

Edited by sterlingsilver

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That wildlife guy who had a show on the ABC has a Newfoundland who had stem cells injected into her knee joints. She was suffering from very bad Arthritis (she may have had a Cruciate Ligament problem but they didn't say).

They never showed a follow up to her surgery so I have no idea if it was successful. I stopped watching it because I was only interested in the Newfoundland and I thought the guy was a bit of a wanker.

ETA

The show was called "Chris Humfrey's Wild Life".

Edited by dogcentric

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We had a seminar on it at SACA a few months ago. You should be able to get a copy of the DVD if you call Noahs Crossing Vet Clinic. Much cheaper alternative to a hip replacement and a successful trial has been done.

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A friend has just had the treatment for her dog. I mentioned this thread and she said I could pass this on - one of their vet nurses has a 4 y.o. dog (not sure what breed) that couldn't walk 400m without needing to be carried back home, couldn't climb stairs, in/out of car etc., with bad HD. They did the stem cell treatment and now do can go 4km+, in/out of car, completely normal range of movement. Also she's happy for me to pass on her email to sterlingsilver if you'd like to discuss it all with her (she's got copies of studies too) - contact me by PM if you'd like it.

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I was previously working with stem cells, assisting vets with harvesting fat, and processing in the laboratory. I have now moved on to the most scientifically advanced stem cells.

A brief overview of whats available now, but I will write up some more info if people are interested.

I now work for Monash Uni, and we have Allogeneic stem cells available. These are pure stem cells, taken from a donor and grown in culture in the laboratory. The benefits over the old method of harvesting fat are-

No need to cut and scar your dog

No need for full anesthesias

Pure mesenchymal stem cells, not stromal vascular fraction (which is what is isolated when taking your own dogs fat, which has some stem cells)

The original fat is donated by a fully health tested dog under the age of 12months. The cells are younger and work more effectively. An old dog has old stem cells.

and lastly the price is much more affordable, for example a dog under 20kg getting 2 hips treated will be around $1000 to the owner.

Have a look at our website

www.australianstemcells.com.au

Feel free to ask any questions.

If anyone is curious about this in the human world, look around on this website www.mesoblast.com

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a good friend has just had this therapy done for her two yo bitch.. we arehopeful that the outcome will result in a better and hasppier life for her dog..

she is very young and had previously has surgery for fragmented coronoid process.. nasty nasty.

H

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I was previously working with stem cells, assisting vets with harvesting fat, and processing in the laboratory. I have now moved on to the most scientifically advanced stem cells.

A brief overview of whats available now, but I will write up some more info if people are interested.

I now work for Monash Uni, and we have Allogeneic stem cells available. These are pure stem cells, taken from a donor and grown in culture in the laboratory. The benefits over the old method of harvesting fat are-

No need to cut and scar your dog

No need for full anesthesias

Pure mesenchymal stem cells, not stromal vascular fraction (which is what is isolated when taking your own dogs fat, which has some stem cells)

The original fat is donated by a fully health tested dog under the age of 12months. The cells are younger and work more effectively. An old dog has old stem cells.

and lastly the price is much more affordable, for example a dog under 20kg getting 2 hips treated will be around $1000 to the owner.

Have a look at our website

www.australianstemcells.com.au

Feel free to ask any questions.

If anyone is curious about this in the human world, look around on this website www.mesoblast.com

Thankyou for this info.

Has there been a lot of success with the treatment? With long term benefit?

Where do vets get the donor cells from?Whose dogs do they use for this?

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Monash Uni have a vet who looks out for when a suitable dog comes in for a spey, the owners are offered to have the spey done for free if they allow about 1/3 specimen jar of fat to be removed.

One donation of fat grows enough cells for, on average, 2000 single doses. A single dose is equivalent to one joint being treated.

Two vets have been trialling, one in NSW and one in Victoria. More so to see what dosages (ie number of cells) work for each size dog etc.

We are partnered with Vet Stem in the US, they have completed the most trials.

The difficult thing has been that stem cells have always been borne from universities and scientific research. So the money hasn't been there to pour into trials. Unlike pharmaceutical companies where satisfying the consumer, and generating sales, is the main goal. Still, trials are very important no doubt.

Here is one of our partner's trials http://www.vet-stem.com/images/7605-0019-001%20Double%20Blinded%20Study%20-%20Canine.pdf

That is for autogolous treatment however, as allogeneic is the more recent development.

We can still culture your own dogs cells too. So if the thought of an allogeneic transplant is not something you want, we can take you own dogs fat, and expand it in culture. Thus returning many millions of mesenchymal stem cells into each joint, and cryofreezing the rest.

Some of our scientists are working with renal specialists to work towards repairing damaged kidneys, and our two trial vets are getting promising results from the first few congestive heart failure treatments done.

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I have been told the benefits for stem cell therapy for something such as arthrits are only seen for 6 months, then the dog reverts to the way it was prior to stem cell therapy, is this true?

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Curious . . . I'd think they'd be using foetal stem cells for allogenic . . . you wouldn't have right to life opposition to using foetal tissue from bitches speyed while preggers.

Good to hear this is working and that tissue acquisition is reasonably simple.

Monash Uni have a vet who looks out for when a suitable dog comes in for a spey, the owners are offered to have the spey done for free if they allow about 1/3 specimen jar of fat to be removed.

One donation of fat grows enough cells for, on average, 2000 single doses. A single dose is equivalent to one joint being treated.

Two vets have been trialling, one in NSW and one in Victoria. More so to see what dosages (ie number of cells) work for each size dog etc.

We are partnered with Vet Stem in the US, they have completed the most trials.

The difficult thing has been that stem cells have always been borne from universities and scientific research. So the money hasn't been there to pour into trials. Unlike pharmaceutical companies where satisfying the consumer, and generating sales, is the main goal. Still, trials are very important no doubt.

Here is one of our partner's trials http://www.vet-stem....0-%20Canine.pdf

That is for autogolous treatment however, as allogeneic is the more recent development.

We can still culture your own dogs cells too. So if the thought of an allogeneic transplant is not something you want, we can take you own dogs fat, and expand it in culture. Thus returning many millions of mesenchymal stem cells into each joint, and cryofreezing the rest.

Some of our scientists are working with renal specialists to work towards repairing damaged kidneys, and our two trial vets are getting promising results from the first few congestive heart failure treatments done.

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My vet has been doing trials for arthritis, i have talked to the vets about it and have also talked to the dog owners, they are all very happy with the results

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Hi Sterling Silver,

The company that I work for is called Regeneus. We have been doing stem cell therapy in dogs in Australia for the last 3 years (called AdiCell) and have treated over 350 animals. We are now doing work as well on people with arthritis (called HiQCell) with very similar results.

We try hard to track every dog that has been treated (some owners do not respond). Of these dogs, over 80% of owners think that their dog has improved. The biggest improvement seems to be in terms of pain relief, however there are also improvements in lameness, endurance, mobility, and quality of life.

Have a look at our website for more information. www.regeneus.com.au

DuncT

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I have heard a lot about stem cell research in dogs and thought it was the next big thing, but recently I have been told it may not be.

Has anyone has any success with this procedure?

How expensive were the treatments?

As others have said, it may depend on what you want to treat, however I had it done on my SBT pup (see thread) adicell and I can now say, yes absolutely it works.

Mine was done through Regenous at Southpaws in Melbourne. After trying lots of different things, Oscar can now run (for shortish periods, as I don't want to push my luck) and doesn't suffer later like he used to.

What's even better, Petplan paid for the procedure too!!!!!

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I heard yesterday that Applecross vers in WA do stem cell treatment now as a friends dig tore the collateral ligament and now the cruciate in the same leg is going..

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My girl is booked in for Stem Cell Treatment in December, I so hope the results are positive

Edited by BigDaz

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