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Lymphoid Hyperplasia


kayla1
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Maxie has a lump under his skin on his flank. The vet did a FNA and got a couple of samples, and the results from pathology have come back as lymphoid hyperplasia. The cause is unknown, but the vet thinks the results at this stage are 'encouraging' and to monitor for a week to see if it changes.

I've done a search on here and can't find much at all. Don't suppose anyone knows anything about lymphoid hyperplasia? If so, how did you treat it?

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Hi, can't help you but my dog is off to the vet on the weekend to have a similar sounding lump looked at, although hers is on the top of her ribcage near the spine. This lump just sprang up out of nowhere and isn't painful. She is not even 2yo :(

Just wondering if the vet looked at the FNA calls themselves or sent them off? Hope everything works out ok for your dog

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I'd never heard of it either! I'm not finding much treatment info on google.

The vet looked at the FNA samples and ruled out lipoma, foreign body, and MCT, but apart from that it was inconclusive. So it was sent to pathology.

It's a firm oval-shaped lump and feels different to the lipomas that my other dog had - they were softer and moveable. It doesn't seem to be bothering him and he's acting normally.

DesertDobes, I hope your girl's lump turns out to be nothing.

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I did a Google of Lymphoid Hyperplasia, sounds like people and any animal with a lymphatic system can get it. I thought it sounds like they can be just a reaction to producing lots of T cells. I guess your vet would need to find out why the T cells are being produced if it doesn't go in the next week? Thats what I got from Dr. Google lol. Hope they settle over the next week Kayla1

My dogs lump is very hard like cartilage and firmly attached to her ribs, kind of like a ball bearing underneath the skin. She has been fine otherwise but the location and the speed at which it came up have me worried.

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One of my previous young bitches was diagnosed with Follicular Lymphoid Hyperplasia, somewhere between rear of her throat and nasal passage. There was no treatment offered for this and had we not been doing exploratory procedure surrounding her brachycephalic syndrome, we probably would not have know about it.

The specialists (two did this procedure at the same time - one throat and one nose specialist) said that the hyperplasia was most likely caused by the throat obstructions (elongated palet and everted laryngeal saccules and enlarged tonsils or possibly even allergy related. Either way, they did say that not a huge amount was known but because of the reactive cells, one could not rule out that this may be the start of cancer.

Obviously very different in positioning, so no doubt different in treatment, causation and prognosis.

Best wishes.

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I've done a search on here and can't find much at all. Don't suppose anyone knows anything about lymphoid hyperplasia? If so, how did you treat it?

Good luck, it's hard when your dog gets diagnosed with something very uncommon.

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Thanks Dyzney and Rebanne. DesertDobes, glad to hear your girl's lump is nothing to worry about.

I've spoken to a couple of vets and they've never seen lymphoid hyperplasia in the location where Maxie's lump is, so they're going to try to find out if there have been any other cases reported. I'm monitoring for the next few days and if there is no change will commence antibiotics. But at the moment, we have no clue as to what is causing it unfortunately.

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  • 4 weeks later...

Well antibiotics didn't seem to help, and there have been no other reported cases of it occurring in the region where Maxie's lump is. The lump was smaller after the first sample was taken, now it's larger again. So Maxie is now booked in to have it removed, and it will be sent to pathology for further testing. Hopefully that will give us some answers as to what the cause is.

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  • 2 weeks later...

The biopsy results have come back as soft tissue sarcoma. :cry::cry:

I'm still in shock because this result is so unexpected. No cancer cells showed up in the FNA samples, only lymphocytes. Apparently it's an unusual situation and it's possible that the lymphocytes are there because they are attacking the tumour.

So Maxie has to have surgery to remove more surrounding tissue, and because the tumour was in the muscle, this means removing part of his stomach muscle.

I was so excited about going to the vet tomorrow and finally getting his drain taken out from the lump removal op, now I feel awful that he'll have to go through more surgery, and xrays to see if it has spread. :cry:

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The biopsy results have come back as soft tissue sarcoma. :cry::cry:

I'm still in shock because this result is so unexpected. No cancer cells showed up in the FNA samples, only lymphocytes. Apparently it's an unusual situation and it's possible that the lymphocytes are there because they are attacking the tumour.

So Maxie has to have surgery to remove more surrounding tissue, and because the tumour was in the muscle, this means removing part of his stomach muscle.

I was so excited about going to the vet tomorrow and finally getting his drain taken out from the lump removal op, now I feel awful that he'll have to go through more surgery, and xrays to see if it has spread. :cry:

So sorry about the unexpected path results Kayla :cry: When will Maxie have further surgery? I hope the sarcoma hasn't spread to surrounding tissue. Please keep us posted about your boy.

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My dogs lump is very hard like cartilage and firmly attached to her ribs, kind of like a ball bearing underneath the skin. She has been fine otherwise but the location and the speed at which it came up have me worried.

DD this sounds very much like what my girl has and pathology showed that it was a benign granuloma - auto immune induced. The vet was loathe to remove it because of where it is - on the power rim of the eye. Actually she has 2 the other above the eye and had a third removed before these two appeared suddenly.

I'm now having these treated by an holistic vet who is using acupuncture, laser treatment and herbs. Only a week into treatment at this stage.

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Thanks for your thoughts cavNrott and Airedaler.

cavNrott, I'm hoping to get it done this week. I'll call a couple of the specialist oncology centres tomorrow. The margins were very narrow so the sooner the better. Though I don't blame the vet for taking narrow margins, because at the time there was no indication of sarcoma so no reason to take wide margins.

The FNA was taken with Maxie sedated, and a couple of samples were taken, and all that showed up was lymphocytes. The sarcoma was not picked up by the FNA. I don't know if this is common with sarcomas, but it's pretty scary to think of what could happen if someone relied on that and nothing further was done.

It's a grade 2, which is some good news, but it's extensively inflamed. Because of the lymphocytes, it's possible that it's a lymph node that was infiltrated by the sarcoma. But nobody knows and the cause of the inflammation is unclear. So I really hope it hasn't spread, and that the surgeon is able to take wide margins.

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Thanks for your thoughts cavNrott and Airedaler.

cavNrott, I'm hoping to get it done this week. I'll call a couple of the specialist oncology centres tomorrow. The margins were very narrow so the sooner the better. Though I don't blame the vet for taking narrow margins, because at the time there was no indication of sarcoma so no reason to take wide margins.

The FNA was taken with Maxie sedated, and a couple of samples were taken, and all that showed up was lymphocytes. The sarcoma was not picked up by the FNA. I don't know if this is common with sarcomas, but it's pretty scary to think of what could happen if someone relied on that and nothing further was done.

It's a grade 2, which is some good news, but it's extensively inflamed. Because of the lymphocytes, it's possible that it's a lymph node that was infiltrated by the sarcoma. But nobody knows and the cause of the inflammation is unclear. So I really hope it hasn't spread, and that the surgeon is able to take wide margins.

Kayla your vet will refer to you an oncologist. You'll need the referral to consult with an oncologist.

When my dog was diagnosed with a malignancy we were referred to the Veterinary Specialist Centre in Glen Waverley, which was local for me. The oncology team there were wonderful and I credit the oncologist who was caring for Sophie (my Rottweiler) with assisting her (GrIV tumour) to live happily and pain free for another 12 months. Her initial prognosis was a month or two at most.

The Veterinary Specialist Centre has the Glen Waverley branch and another branch in Essendon.

Though your vet took narrow margins, where the margins clear?

I know you're probably feeling overwhelmed with all you are dealing with. I hope for the best and ask that you please keep us posted as you travel this journey with your dog.

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Thanks persephone and VizslaMomma, and thanks for the info cavNrott.

Actually Melb Vet Specialist was one of the centres I was going to call. I remembered they have oncology as I’ve seen the dermatologists there before. I heard or read somewhere that the oncologists are really busy(?), so I was going to call to see how quickly I could get in before asking my vet for referral. I’m just feeling really pressured time-wise and it has sent my head spinning.

It's good to hear of a positive experience with the oncology team there, though obviously under sad circumstances for you. :(

The pathologist report says neoplastic tissue extends to within 1mm of biopsy margin – doesn’t say clear – so I assume the margins are not clear. Which I guess is why the vets here have recommended further surgery asap.

My regular vet has suggested one of the other vets down here on the Peninsula do the surgery, but he's not an oncologist and the clinic is not staffed overnight. So that's why I thought either Glen Waverley, or perhaps South Paws (which I've never been to before). Just trying to work it so the next surgery has the best chance of success, and fairly quickly.

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