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Megan2010

I Almost Killed My Dog By Giving Him Fish Oil Tablets :(

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My much loved Neapolitan Mastiff is now 3 years old, but he very nearly didn't make it to his 3rd birthday due to the essential fatty acids contained in fish oil tablets, this is his story:

Neo is a beautiful dog, a much loved member of our family. His favourite activities include stealing my shoes, long walks, socialising with other dogs at the park, sitting under the mulberry tree eagerly awaiting ripe mulberries to drop off for a snack, car drives and relaxing on the couch with his head on my lap.

His dislikes include, bath time, swimming, cats, vacuum cleaners, lawn mowers and being roused on when naughty (when roused on he gets the sulks and goes and sits in another room until I come and apologise lol).

He's very spoiled, I make his own food, he has a very balanced diet, lots of fresh meats, fresh fruits and fresh veggies, he's never spent a night outdoors in his life.

A few months ago I noticed he was seeming a little lame on his back legs, I took him to the local vet, who examined him, couldn't see anything wrong, said it was "probably just arthritis". I asked for a referral to an Orthopaedic specialist to make sure.

The specialist couldn't see anything obviously wrong with him, and said it's most likely arthritis with him being such a large dog, and we were prescribed with Rimadyl for the pain and inflammation.

Both the vet and the specialist said I should also supplement him with Fish Oil and Glucosamine. I mentioned Neo was already taking fish oil and had been all his life as the breeder said they were great for healthy joints and a beautiful coat, with regards to the fish oil I told them he was having 8 capsules a day (keeping in mind he's an 80kg dog, 4 each meal), both vets said this was a good amount.

Despite the Glucosmine Neo's condition deteriorated gradually over the next few weeks, he had so much trouble standing up and sitting down, he seemed to be in pain. I went back to the specialist who gave Neo a prescription for Tramadol in addition to the Rimadyl. He said if there was no improvement he would need to do exploratory surgery and take x-rays and biopsies etc. Unfortunately as he is a specialist he was very busy with emergency cases so this couldn't be for another week.

The next day Neo's condition had worsened, he wasn't himself, he was puffing without exercise, he was pretty much paralysed in the back legs now, i had to help him up a lot of the time and he was yelping in agony when touched and even randomly yelping when resting.

I took him to the local vet and demanded x-rays of his legs, hips and spine be done, they found some spondylosis (they said this is like arthritis on his spine), and deduced this was the cause of his pain. They said the rest of his life would be about pain management now, and was prescribed some heavy pain killers, Valium and more Rimadyl.

I didn't accept this diagnosis and took him to see yet another vet for a second opinion. This vet was great, he actually seemed to care about Neo. I asked for a full ultrasound to be done on Neo to make sure he didn't have any tumours, as this vet said the amount of pain he was in didn't seem to correlate to the small amount of spondylosis on his spine.

A nervous day spent awaiting the results and thankfully the ultrasound came back clear. We discussed the options available including low dose short term only steroids and also stem cell therapy, I decided to think about both, still not certain in my mind it was arthritis. We also discussed supplements such as glucosamine, fish oil, Sasha's blend (green lipped mussel) and he even suggested milk thistle for Neo's liver if he took the steroids.

After our visit to this vet I also took Neo to a naturopath, the naturopath said fish oil was great for dogs, also glucosamine, he said the human stuff was better than the pet stuff and cheaper. He also gave us some herbal treatments for pain management.

Still not content (the amount of pain he was in seemed enormous given that he was on heavy pain killers), he also seemed to be in pain everywhere, not just his back legs or back, it just didn't make sense to me, and I wasn't ready to give up on Neo and resign him to a life of pain management and horrible drugs until i had a definitive diagnosis, not a "maybe" or "probably".

So i got on the internet and spent several days and sleepless nights researching causes of extreme pain and lameness, when finally I came across several articles about "vitamin E deficiency", and then the more researched the more everything fit!

The articles said it was very rare in dogs (it's apparently seen more often in cats that eat tinned tuna) and extremely hard to diagnose, but symptoms included:

- severe pain

- hyper sensitivity to pain

- lack of muscle tone

- lameness

- paralysis

- skeletal problems

- muscle weakness

- leg/feet swelling

- edemas

- weight loss (although no loss of appetite)

- cataracts

- premature aging

I could tick pretty much every box except the cataracts, Neo had 2 edemas earlier in the year in both his back legs, at the time the vets couldn't explain them, biopsies were negative for nasties, they were just "inflammatory fluid", I was told they were most likely bites, although they appeared to come from the "inside" of the leg, ie there was never any "bite" mark, no damage to the external skin, I had no reason to think these were related in any way to his "arthritis" which started months later.

As for the premature aging his face was also going grey already, which I thought was unusual for a 3 year old dog, which was one of the reasons I asked the vets to ultrasound his organs for tumours.

The good news is, as soon as I read these articles and all the puzzle pieces just fell into place I drove straight to the 24/7 chemist, bought vitamin E capsules (the natural vitamin E) and started him on them immediately and threw out the fish oil tablets. Within 24 hours he was able to get himself up without any help, later the next day he was up and walking around again albeit stiffly and limping, within 2 days he was barely limping and all the yelping had stopped, he was also able to stand up and sit down easily again.

After 3 days the limp was gone and his pain was almost gone, i started reducing his Rimadyl and pain killers gradually and after only 1 week he was running, jumping, playing, back to his old regular cheeky self again, and he was free of all medications!!! :laugh:

Even with the rain this week and colder weather he hasn't shown any signs of "arthritis", he's like a puppy (albeit a giant one) again! :) I have my boy back!

2 weeks ago a guy from work told me about his 10 year old Maltese, who was collapsing, lame, had cataracts, he was being tested for "Cushing's disease", he'd already being tested for spleen cancer and diabetes. I curiously asked him if he fed his boy fish oil tablets, he said yes he was fed 2 per meal for his arthritis, had done so for years.

I suggested 4 fish oil tablets a day for a little dog like that might be a worry, and suggested he stop the fish oil and get the vet to test for vitamin E deficiency instead, and sure enough the test was positive, he had acute vitamin e deficiency. Within a week his boy was cured too.

So this got me wondering, if a guy i work with also has this problem with his puppy, just how many other peoples dogs is this happening to? Are vets diagnosing any general unexplained pain as just blanket "arthritis"? Are dogs being put to sleep because they have "chronic arthritis" when all they need is a $5 bottle of vitamins for a complete cure? Are we killing our best friends with love (aka fish oil/omega 3)?

I decided to write this post in the hope that it will save a dogs life. This information is really hard to find and studies are only just starting to come out about the dangers of over supplementing fish oils without balancing them with vitamin E, and most of those are human studies, and humans generally get much more vitamin e in their diets than dogs do. Vets don't seem to be aware of it, in fact, they seem to be promoting the use of fish oil.

As a giant breed Neo was told by his breeders to take fish oil as a preventative and for a nice coat, and his vets all agreed, yet this almost killed him. Fish oil isn't as safe as vitamin sellers would have people believe.

Below I'll go into some more detail about what my research turned up for those who are interested. I'm not a vet or a scientist so please do your own research and speak to a decent vet about it who is aware of vitamin E deficiency before supplementing your dog with anything!

From what I've read vitamin E deficiency can be caused by any of the following essential fatty acid containing products, but especially combinations of them:

- Fish Oil supplements

- Flaxseed Oil supplements

- Other omega fatty acid supplements EPA/DHA/OMEGA3 etc

- Frozen fish

- Canned fish

- Green Lipped Mussel products (Sasha's Blend, Technyflex, Glyde etc)

- Some dogs have digestive problems which prevent them from digesting fats (and consequentially vitamin e) properly.

- Diet (most dogs don't eat vitamin e rich foods like nuts, wheatgerm, plant oils etc)

(Note: Apparently fresh raw fish is ok because it contains vitamin E naturally, but freezing, cooking, canning, processing it kills the viatmin E but leaves the omega 3's intact.)

You can avoid vitamin E deficiency in your dogs by simply supplementing them with SMALL amounts of vitamin E if you give them fish oil or buy a decent brand of fish oil (hard in Australia) that has enough vitamin E added to offset the depletion (I understand it's as little as 4 iu - 10 iu of natural vitamin E per 1000 mg of fish oil is all that's required to prevent the fish oil from depleting a dog's vitamin E levels). But the amount you need to give your dog will obviously depend on how big the dog is, and how much essential fatty acid containing products and foods with vitamin E they already consume as part of their diet.

So don't run out and buy 1000 iu vitamin e tablets and give them to your dogs! Too much fish oils (essential fatty acids) deplete the body of vitamin E, but too much vitamin E will apparently increase the dog's requirements for vitamin A, vitamin K and vitamin D! (It's quite a balancing act, which is why supplements can be dangerous!) Also vitamin E in mega doses like 1000 iu's can cause bleeding/haemorrhaging because it thins the blood.

Below is a quote from the website (http://mydogyogi.wordpress.com/) i found the most useful, and the one that saved my Neo's life:

"When giving fish oil (to your dog) on a regular basis extra vitamin E, an important fat-soluble vitamin and antioxidant, is typically needed. Fish oil oxidizes easily and the (dog's) body will use up its stores of vitamin E when processing fish oil. Therefore sufficient vitamin E is required in the diet to prevent a vitamin E deficiency in your dog.

Most fish oil supplements contain additional vitamin E, though this is typically only enough to preserve the product and not a significant source for the body to use. It is better to supplement natural vitamin E instead of synthetic, so when buying vitamin E look closely at the label. Natural vitamin E is listed as d-alpha-tocopherol and synthetic vitamin E is listed as dl-alpha-tocopherol. One little “L” makes a big difference is how effectively the (dog's) body can use it.

I encourage you to work together with your veterinarian to determine if a fish oil supplement is okay for your dog and to find out dosage information for both the fish oil and vitamin E."

Some references for those who would like to learn more are below:

http://www.ehow.com/facts_7291768_do-suppl...eficiency_.html

http://www.xtend-life.com/Blog/10-11-23/Do...n_E_levels.aspx

http://resources.metapress.com/pdf-preview...mp;size=largest

http://mydogyogi.wordpress.com/

http://www.ncbi.nlm.nih.gov/pmc/articles/P...00137-0031a.pdf

I hope the information I've collected above proves useful for some other dogs out there, and their owners. The 3 thing I've learnt from all this are:

- Supplements can be dangerous, even "SAFE" ones.

- Vets are human, they're not always right and they can't be expected to know everything, as an owner you know your pet better than anyone else.

- Never give up, seek second opinions, do your own research.

M :p

Oh and a quick edit, don't let this put you off fish oil tablets either, Neo has always had the most beautiful coat, people comment on it all the time. Just make sure you give your pups enough vitamin E to balance them!

Edited by Megan2010

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Interesting. I have heard of vit E deficiency causing problems in pet cats (usually in the form of pansteititis), but not dogs. Glad your dog recovered.

I do already give my dog a 200IU of vit E every week to go along with her fish body oil, and recommend that other owners give E too if they feed much fish body oil or other PUFA. From what I know, fish oil that has turned rancid/has oxidised is much more of an issue than the fresh stuff, since more E is needed to process it.

I wonder if your dog was also low in Se? Se has a sparing effect on vit E demand.

Edited by Staranais

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I am glad you made this post. This was something I discovered on a US breed specific dog forum after I came across many discussions the need to add vit E. I am sorry your dog had to suffer like this until the answers were found.

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JulesP   

Lots of vitamins need other vitamins or can block the absorption of them. I just gave myself magnesium deficiency by taking big does of Vit D (under doctors orders).

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Moselle   

Thank you Megan for starting this thread and bringing such an important factor to our attention, who would have known ?? This has been of immense help, kudos to you :laugh:

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Aziah   

I'm glad your Neo is ok now...

A timely reminder that it's so important to research any supplements before using them on a daily basis :laugh:

Edited by Aziah

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Nekhbet   

also another reason that if you're making a dog a home made diet to ensure it is not lacking in essential vitamins and minerals. This is why I stick to dry food especially in growing dogs or I reccomend people buy something like the Vets All Natural Health Booster to make sure your dog is getting what it needs irrespective of the ingredients you purchase.

I also recommend the ethical nutrients high strength liquid fish oil instead of the capsules. Yes it has to be in the fridge but a cap full will easily do a 60kg dog a day

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OSoSwift   

My old dog is on Vit E along with his fish oil and has been so from the beginning as I was aware of the need for vit E, but you are right it is something we should be reminded of and take care to get the balance right

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raz   

2 fish oil caps a meal for a tiny little Malt? Gee even an adult human is told 3 per meal and starting slowly from 1.

Have you been given a diagnosis from your vet about your Neo's reaction?

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toshman   
My much loved Neapolitan Mastiff is now 3 years old, but he very nearly didn't make it to his 3rd birthday due to the essential fatty acids contained in fish oil tablets, this is his story:

<snip>

I decided to write this post in the hope that it will save a dogs life.

Just a question Megan - did you write this post yourself, or did you copy it from an email which does the rounds at various times? Some of your phrases sound rather "fishy" so to speak?

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This is very informative and interesting, thank you for sharing.

My dog isn't on any fish oil, but she is on Glyde which contains Green-lipped mussel, makes me wonder if she needs Vit E supplements in this case..

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Bully   

If supplementing with fish oil vit. E should always be given. Some bottles of fish oil caps state, most don't :laugh:

I always mention to people who give fish oil to supplement with vit. E. Most are unaware :) So glad you boy is better now :p

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OSoSwift   

My dog has heart disease and spinal and other joint arthritis. He is on prednisolone due to spinal cord compression so cannot have any other NSAID, which didn't work when we tried them before the Pred anyway. He has tramal as required but since giving him fish oil among other things he does not need the tramal.

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My much loved Neapolitan Mastiff is now 3 years old, but he very nearly didn't make it to his 3rd birthday due to the essential fatty acids contained in fish oil tablets, this is his story:

<snip>

I decided to write this post in the hope that it will save a dogs life.

Just a question Megan - did you write this post yourself, or did you copy it from an email which does the rounds at various times? Some of your phrases sound rather "fishy" so to speak?

I wrote it myself, except for the bits I put in inverted commas, and I included the reference for that too, and added some references to some of my research down the bottom.

Sorry if it sounded a bit fishy, I have been writing it all week so it might be a bit fragmented!

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If a dogs diet is sufficient why are so many having fish oil added?

My dog has allergies, was told to give him 5 fish oil and 5 evening primrose caps a day by the derm.

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This is very informative and interesting, thank you for sharing.

My dog isn't on any fish oil, but she is on Glyde which contains Green-lipped mussel, makes me wonder if she needs Vit E supplements in this case..

There's probably not enough in Glyde alone to cause any issues, I thought I'd just mention it incase people were giving fish oil and green lipped mussel products together, not realising there were omega3's in the green lipped mussel.

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